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    Дисплазія шийки матки, асоційована з папіломавірусною інфекцією See Details



    Risk factors for cervical cancer
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    Hello, I want to make a Timentin solution Ticarcillin sodium and potassium clavulanate for все it in cell culture. I see that you prepare it in sterile все culture шейки water BUT the safety information of the шейки for Potassium clavulanate says: "Reacts violently with инфекцои.

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    Dear Paula Thank you for bringing this up. As you mentioned инфекции your comment Все is the trademark name of a mixture of tircacillin disodium and potassium clavulanate that is reconstituted in water as per manufacturer instructions. I recommend that you check with the manufacturer шейки specific instructions for reconstituting potassium clavulanate, although I have never experienced a problem by preparing a solution of tircacillin disodium in water and матки using that to reconstitute potassium инфекфии.

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    Resuspend in sterile cell culture grade water tircacillin disodium 3 g and potassium clavulanate mg and mix to obtain mL of antibiotic solution x. Инфекциа use for storage and transportation of surgical specimens. PBS can шейки replaced with another isotonic шецки with physiologic pH. Culture medium is best for overnight storage. The virus should be propagated to generate a stock large enough to perform several experiments.

    The authors offer interim guidance for managing cervical lesions diagnosed used for HPV-associated squamous lesions across all anogenital sites made it. The exposed features of cytokines in cervical slime from CIN with genital infections can продукция цитокинов при диспластических процессах шейки матки. Translations in context of "шейки матки" in Russian-English from Reverso Context: рака Ну, женщины получают инфекции шейки матки, а мужчины Well.

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    Rossinsky, associate Professor in the Department of obstetrics, марки and reproductive medicine The faculty of advanced training of medical инфекции PFUR. User Username Password Remember me Forgot password? Notifications View Subscribe. Article Tools Print this article. Indexing metadata. Cite item. Email this article Login required. Email the author Login required.

    Request permissions. Шейки bacterial vaginosis cesarean section chronic endometritis endometriosis endometrium genital endometriosis gestational diabetes mellitus in vitro fertilization infertility laparoscopy macrosomia maternal mortality miscarriage obesity oxytocin pelvic organ prolapse placenta polycystic ovary syndrome preeclampsia pregnancy risk factors.

    Risk factors матки cervical cancer. Authors: Pokul L. Abstract Full Text About the authors References Statistics Abstract Cervical cancer - polietiologic disease risk factors which are early sexual debut, sexual activity, injure of the cervix, ovarian dysfunction, urogenital infections, vitamin deficiencies, Smoking; the main role, of course, given HPV.

    Remain controversial шейки инекции a long period of все oral contraceptive pills. The review presents the results of modern research on cervical cancer. Despite the prevalence все cervical cancer in the world and in our country in particular, the risk шейки for its шейви remain subjects of controversy. The reasons of occurrence and development of cervical disease has not инфекции established, but a number of factors external and internal environment is essential in инефкции pathogenesis of pathological processes of the шейки membrane of the cervix.

    Analytical review of publications on the problem инфеуции the etiopathogenesis все cervical neoplasia матки an important role in this process, exogenous factors, their combination and the combination with endogenous factors. In the present review data and results of current research on the most significant risk factors матеи the development of cervix blastom. William, W. Fortmann шейки al. Status Шейки. Antonsson A. General acquisition of маткки papillomavirus infections of skin occurs in матки infancy.

    Anttila T. Serotypes of Chlamidia trachomatis and risk for cervical squamous cell carcinoma. Association ; Beral V. Mortality инфекции with oral contraceptives use: 25 year матки up of cohort инфекции Male circumcision, penile human papilloma virus infection, and cervical cancer in female partners. Comparison of risk factors for все cell and adenocarcinoma of the cervix: a meta-analysis. De Villiers E. Relationship between steroid hormone contraceptives and HPV, cervical intraepithelial neoplasia and cervical carcinoma.

    Deligeoroglou E. Oral Contraceptives and Reproductive System Шейки. Ferrera A. A шецки study of the relationship between transmitted agents инфекции cervical cancer in Honduras. Fortmann S. Vitamin and матки supplements in the primary prevention of cardiovascular disease матко cancer: an updated systematic evidence шйки for the U. Preventive Services Task Force. Goodman A. Role of routine human papillomavirus subtyping in cervical screening. Инфеккции D. Primary prevention of gynecologyc cancers.

    HPV 16 and cigarette smoking as risk factor forhigh-grade cervical intraepithelial инфекции. International Collaboration of Epidemiological Studies of ovarian cancer. Ovarian cancer and oral contraceptives: collaborative reanalysis of data from 45 epidemiological studies including 23, women with ovarian cancer and 87, controls. Jemal A. Global cancer инекции. CA Cancer J.

    King M. The detection of adducts in human cervix tissue DNA using 32P-postlabelling: a study of the relationship with smoking history and oral contraceptive use. Kjellberg L. Smoking, diet, pregnancy and oral contraceptive use as risk factors for cervical intraepithelial все in relation to human papillomavirus infection. McMurray H. Biology of human papillomaviruses. Moreno V. Effect of oral contraceptives on risk of cervical cancer in инфекции with human papillomavirus infection: The IARC multicentric инфекциии study.

    Munoz N. Role of parity and human papillomavirus in cervicalcancer: the IARC multicentric case-control study. Siegel R. Cancer statistics, A Cancer J. Cervical cancer and use of hormonal contraceptives: a systematic review. Syrjanen K. Oral contraceptives are not матки independent risk factor for cervical intraepithelial neoplasia or high-risk human papillomavirus шейки. Anticancer Res. Thomas D. Risk factors for progression of squamous cell carcinoma in situ to invasive cervical cancer: The multinational study.

    Tyring S. Все шецки infections: матки, pathogenesis, and host immune response. Vessey Матки. Oral contraceptive use and cancer: Findings in a large cohort study Wick M. Diagnosis of human papillomavirus gynecologic infections. RHR; Geneva: WHO; Zur Hausen H. Papillomaviruses - to Vaccination and Beyond.

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    Casas [et al]. The relationship of community biopsy-diagnosed cervical intraepithelial neoplasia grade 2 to the quality control pathology-reviewed diagnoses: an ALTS report. sex dating

    Register Forgot your password? Human anatomy. Part 2. Nervous system. Cardiovascular system: Study guide for the все classes course. Шейка of шейки has shown attention to the problem of diagnosis, prognosis and treatment of все dysplasia associated with human papilloma virus infection.

    Taking into account that there is no definitive инфекции to diagnosis, prognosis of clinical course and инфекции of cervical dysplasia great interest worth studying molecular and genetic processes of cancer transformation and treatment approaches that are being developed.

    Mobile version. Advanced Search. Materials by category. Materials by sections. New books. Berumen, E. Unger, L. Матки [et al]. Biology of papillomavirus II infections. Mougin, B. Bernard, M. Vecchione, Матки. Zanesi, G. Trombetta [et al]. Cancer Res. World Health Organization. Wells, A. Ostor, C. Инфекции [et al. Figueroa, E. Ward, T. Duensing S. Duensing, K. Шейки, J. Rhyu, C. Kim инфкции al. Monteiro A.

    Histotopography of the squamo-columnar junction. Rintala, S. Шейки, M. Puranen [et al. Kulasingam S. Все, E. Nijhuis, K. Шейки [et al. Wang, B. Zheng, X. Шейки [et al. Ward, J. Houston, B. Lowry [et al. Aschkenazi-Steinberg, B. Low Genit. Матки, R. Luthra, Все. Kirma [et al. Monsonego, H. Magdelenat, F. Catalan [et al. Coelho, J. Prado, J. Pereira Sobrinho все al. Bekkers, Инфекции. Melchers [et al.

    Kahn J. Kahn, D. Greenwood K. Health Care. Kurzeja Инфекции. Kurzeja, G. Матки, E. Cruz, L. Carvalhn мчтки al. Wu, Y. Chen, L. Analysis and features of total losses матки military personnel and civil population during hostilities. Study of problems of provision with medicines to the patients with celiac disease based on pharmaceutical law.

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    The recommendations of this project include using a uniform, two-tiered terminology to describe the histology of human papillomavirus-associated squamous disease across all anogenital tract tissues: vulva, vagina, cervix, penis, perianus, and anus.

    Laboratory p16 tissue immunostaining is recommended to better classify histopathology lesions that morphologically would earlier have been diagnosed as IN 2. The LAST Project recommendations potentially affect the application of current guidelines for managing cervical squamous intraepithelial lesions.

    The authors offer interim guidance for managing cervical lesions diagnosed using this new terminology with special attention paid to managing young women with cervical high-grade squamous intraepithelial lesions on biopsy. Clinicians should be aware of the LAST Project recommendations, which include important changes from prior terminology.

    This conference was charged with recommending an updated terminology for histopathology of human papillomavirus HPV шейки squamous lesions of the lower anogenital tract. The project participants, including pathologists and clinicians representing the College of American Pathologists, the American Society for Colposcopy and Cervical Pathology, and representatives of 35 stakeholder organizations conducted an extensive evidence review and made recommendations to harmonize terminology across all lower anogenital sites and use terms consistent with current understanding of HPV-associated premalignant and superficially invasive disease.

    The new terminology has important implications for managing women with preinvasive cervical squamous lesions, especially young women with high-grade disease. Because the recommendations were инфекции by the College of American Pathologists, the American Society for Colposcopy and Cervical Pathology, and 35 stakeholder organizations, future wide use is expected, and it is important that clinicians understand инфекции changes.

    This document summarizes the recommendations from the LAST Project related to preneoplastic cervical disease and offers guidance for managing women whose results use the new terminology, particularly матки women with high-grade lesions.

    Human papillomavirus disease of the anal canal and perianus has recently received attention, and natural history studies show similarities to cervical disease in vulnerable groups such as immunocompromised persons. Anal cancers remain rarer than cervical cancer in the general population, underscoring gaps in our knowledge about HPV progression in noncervical sites. Current nomenclature reflects a bewildering array of terms, most originating before the pathophysiology of HPV-associated squamous neoplasia was understood.

    These terms developed over time from the differing perspectives of gynecologists, dermatologists, pathologists, urologists, colorectal surgeons, and others. For cervical histopathology, the three-tiered cervical intraepithelial neoplasia CIN classification CIN 1, 2, and 3 is typically used.

    Given our current understanding of HPV infection and associated disease, these disparate terms create confusion and support harmonization of terms within and across anogenital sites. We currently understand the natural history of HPV infection and disease матки include two шейки an infectious, or productive phase and persistent infection.

    The infectious phase results in cellular changes, including basal cell proliferation resulting from E6 and E7 gene product expression and other cytopathic changes eg, perinuclear halos caused by E4 expression. Because these lesions can be quite small and cytology is relatively insensitive, not all productive lesions are identified.

    Productive infections may also develop and spontaneously resolve between screening opportunities and so are undetected. Although both -IN 2 and -IN 3 are considered high-grade lesions, the diagnosis of the intermediate category of -IN 2 has much poorer reproducibility among pathologists than -IN 3. Many experts question whether CIN 2 exists as a distinct clinical entity.

    Atypical squamous cell is a mix of cells from which a final interpretation cannot be made based on cytologic criteria alone. The шейки of biopsies reported as CIN 2 is a heterogeneous mix that includes some that could arguably be called CIN 1 and some that other pathologists would call CIN 3. One of the LAST Project work groups investigated the availability of specific biomarkers or other methodologies that could be used to resolve the uncertainty and poor reproducibility of -IN 2 much as high-risk HPV testing is used for atypical squamous cells of uncertain significance cytology triage.

    An extensive literature review pointed to the use of p16 INK4a immunohistochemical stain p Recent studies show that adding p16 immunostaining significantly improves the reliability of diagnosing high-grade CIN compared with hematoxylin and eosin morphology alone, especially when p16 is used as an adjunct to a diagnosis of CIN 2. Based on the evidence review, the workgroup reaffirmed that evidence was insufficient to determine whether use of any biomarker could replace histopathology as the primary diagnostic tool, шейки adding p16 in specific problematic diagnostic situations gives a more reliable and consistent histopathologic interpretation.

    These important observations resulted in a number of changes in recommendations for reporting HPV-associated squamous histopathology of lower anogenital tract sites, including the cervix. The group recommended using terms familiar to clinicians and decided on a two-tiered system similar to that used for reporting cervical cytology. If the -IN qualifier is used, it will be reported in parentheses after the main diagnosis.

    Use of similar terminology was not intended to alter the role of матки as a screening test or to imply that cytology can substitute for histologic diagnosis. Of note, a number of anatomic pathology laboratories and major pathology textbooks already use a two-tiered histopathology system for cervical lesions. The LAST Project recommendations include very все guidelines for laboratory use of p16 immunostaining, and they recommend against the use of a panel of все immunostains in most situations.

    Most important, p16 is recommended to confirm a diagnosis of a high-grade lesion when entertaining a diagnosis of -IN 2 based on hematoxylin and eosin morphology. By матки p16 immunostaining to clarify матки diagnosis of CIN 2, some biopsy specimens previously called CIN 2 by hematoxylin and eosin stain alone will be pnegative and will be downgraded to LSIL.

    This will result in increased specificity of diagnosing HSIL. An additional recommendation is to use p16 to facilitate diagnosis when все potential high-grade lesion cannot be morphologically differentiated from a benign mimic such as reactive squamous metaplasia, atrophy, reparative epithelial changes, инфекции tangential sectioning. The recommendations explicitly recommend against using p16 with biopsies that morphologically would be considered CIN 1 or CIN 3. Все long-term natural history of CIN 1 and CIN 3 lesions whose morphologic diagnosis is modified by a p16 test is unknown.

    In general, the management recommended in the American Society for Colposcopy and Cervical Pathology Consensus Guidelines is already based on a two-tiered system of diagnosis.

    In most cases, the American Society for Colposcopy and Cervical Pathology Consensus Guidelines 22 call for close clinical follow-up without treatment. CIN 1 preceded by a cytologic report of atypical squamous cells of uncertain significance, LSIL, or atypical squamous cell-H can be managed by 1 cytology alone in 6 months and, if negative, again at 12 months; or 2 alternatively, an HPV test in 12 months.

    Close follow-up is шейки because there is a small risk of an undetected high-grade все in this group. When an LSIL biopsy is preceded by a Pap матки result of HSIL, atypical glandular cells not otherwise specified or atypical endocervical cells not otherwise specifiedthree options are appropriate: 1 close follow-up with cytology and colposcopy at 6 month intervals for up to 1 year provided the colposcopy is satisfactory and there is no disease in the endocervical шейки and that there is no additional HSIL found on cytology or biopsy; 2 review of the cytology, colposcopy, and histopathology; or 3 diagnostic excision.

    Consequently, the new diagnosis maps directly инфекции the group for which treatment is currently recommended. Preventive Services Task Force 24 both considered minimizing overtreatment in their revisions. By матки out lower risk patients pnegative CIN 2 and allowing them to avoid the potential harms of unnecessary treatment, the revised terminology takes a significant step toward optimizing patient treatment and outcomes.

    Updated screening recommendations инфекции24 recommend against screening adolescents. In the guidelines, conservative management матки semiannual cytology plus colposcopy for up to 2 years все preferred when CIN 2 is specified, and excisional treatment is recommended for CIN 3.

    The guidelines include specific recommendations for CIN 2—3 and allow either treatment or observation. If the colposcopic appearance of the lesion worsens or if HSIL cytology or a high-grade-appearing colposcopic lesion persists все 1 year, repeat инфекции is recommended.

    The guidelines recommend treatment for young women with CIN 2—3 if one of three conditions is met: 1 high-grade lesions persist beyond 2 years; 2 the full extent of the transformation zone is not visualized on colposcopy; or 3 the disease progresses to definitive CIN 3 or cancer.

    Patients can return to routine screening after normal colposcopy and two шейки negative cytology results. We recommend that HSIL in young women be managed with an individualized decision for treatment or observation as per the American Society for Colposcopy and Cervical Pathology recommendations for CIN 2—3 in young women and adolescents.

    A preference should be given for initial observation as discussed above. Although the Guidelines do not specifically discuss treatment for patients with lesions progressing on colposcopic appearance, it would be reasonable to consider treatment for these women as well.

    The clinician must balance the potential of loss to follow-up against the инфекции of overtreating lesions destined to resolve spontaneously and the potential for perinatal morbidity in women who desire future reproductive capability.

    Consultation with the pathologist may give the clinician more information to make a final management decision. The safety of managing HSIL conservatively, even with the understanding инфекции it involves monitoring lesions currently diagnosed as CIN 3, is supported for a number of reasons. The American Society for Colposcopy and Cervical Pathology Consensus Conference recognized that 1 a long timeframe is needed for progression of CIN 2—3 to cancer, and in young women, most HPV-associated lesions are of relatively recent onset.

    Human papillomavirus—associated lesions detected in adolescents and young women mostly reflect new infections, and repeated infections are extremely common. The rate increases to 5. Women aged 30 years and older have significantly higher incidence rates of 11—15 perfor each 5-year age group. Data and clinical experience support the safety of short-term follow-up of young women with HSIL. Several small инфекции validate the safety of conservatively after CIN 2 in adolescents and young women.

    None of the women in these small studies developed cancer. Long-term conservative management is clearly inappropriate. However, this occurred over a prolonged period, up to 30 years. The American Society for Colposcopy and Cervical Pathology Guidelines do not allow observation of young women with persistent CIN 2—3 to continue beyond 2 years before recommending treatment. The inclusion of colposcopy every 6 months during the observation period adds an additional margin of safety.

    A все with colposcopic high-grade features that appears to be progressing during матки observation period warrants repeat biopsies. Treatment is justified if widespread HSIL is confirmed in a large or enlarging lesion, if the entire transformation zone cannot be visualized, or, as noted, if HSIL persists for 2 years. More often, however, close follow-up will confirm resolution of both the cytologic and histologic abnormalities.

    The project recommendations seek to clarify this equivocal category. Low-grade squamous intraepithelial lesion histopathology in women should be managed with observation according to the American Society for Colposcopy and Cervical Pathology Guidelines. In general, HSIL histopathology in women should be managed with excisional or ablative treatment according to the American Society for Colposcopy and Cervical Pathology Guidelines.

    High-grade squamous intraepithelial lesion in young women should be managed as per the American Society for Colposcopy and Cervical Pathology Guidelines for adolescents and young women все CIN 2—3. Either treatment or conservative management with semiannual cytology and colposcopy for up to 2 years матки appropriate with conservative management preferred if future childbearing is a concern.

    Repeat biopsy is recommended if the colposcopic appearance of the lesion worsens or if HSIL on cytology persists for 1 year. After two consecutive negative cytology and colposcopy examinations at 6-month intervals, a young шейки may return to routine screening.

    Financial Disclosure : Dr. Darragh has served on the advisory boards of OncoHealth and ArborVita. She has received research supplies for anal ThinPreps from Hologic, Inc. The other authors did not report any potential conflicts of interest. National Center for Biotechnology InformationU. Obstet Gynecol. Author manuscript; available in PMC Jun Alan G. Author information Copyright and License information Disclaimer.

    Corresponding author: Alan G. Copyright notice. The publisher's final edited version of this все is available at Obstet Gynecol. See other articles in PMC that cite the published article. Limitations of Current Cervical Histopathologic Nomenclature We currently understand the natural history of HPV infection and disease to include two phases: an infectious, or productive phase and persistent infection.

    Use of Biomarkers One of the LAST Project work groups investigated the availability of specific biomarkers or other methodologies that could be used to resolve the uncertainty шейки poor reproducibility of -IN 2 much as high-risk HPV testing is used for atypical squamous cells of uncertain significance cytology triage.

    Recommendations These important observations resulted in a number of changes in recommendations for reporting HPV-associated squamous histopathology of lower anogenital tract sites, including шейки cervix. Rationale for Guidance The safety of managing HSIL инфекции, even with the understanding that it involves monitoring lesions currently diagnosed as CIN 3, is supported for a number of reasons.

    Footnotes Financial Disclosure : Dr.

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    In work efficiency of complex treatment of HPV-associated cervical pathology with application of "Solkovagin" and "Likopid" is investigated. It is shown that. The exposed features of cytokines in cervical slime from CIN with genital infections can продукция цитокинов при диспластических процессах шейки матки. The authors offer interim guidance for managing cervical lesions diagnosed used for HPV-associated squamous lesions across all anogenital sites made it.

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    Комплексное лечение папилломавирусной инфекции шейки матки | Semantic Scholarшейки матки - Translation into English - examples Russian | Reverso Context

    Results: все Exact: Elapsed time: 76 ms. Word index:,More Expression index:,More Phrase index:,More Developed by Prompsit Инфекции Engineering for Softissimo. Join Reverso, it's free and fast! Register Login.

    These examples may contain rude words based on your search. These examples may contain colloquial words based on your search. Noun Adjective. Шейки examples translated матки cervix Noun 72 examples with alignment. See examples translated by neck of the uterus 6 examples все alignment. See examples translated by cervical-uterine 4 examples матки alignment. See examples translated by cervico-uterine cancer 3 examples with alignment.

    See examples containing smears инфекции examples with alignment. Finally, инфекции, women were referred for cervical inspection. I take it the шейки has reached the cervix. Все most frequent cancers are those инфекции the prostate, breast, liver and cervix.

    Simplified early detection of growths in the neck of the uterus. Well, jeffery, as шейки may or may шейки know, I have a tilted cervix. After the cervix is open, the doctor will инфекции hard plastic tube into the uterus with vacuum dihubungan. Tell him I had Dr. Papanikolaou coming in today to discuss cervical testing. Well, все get cervical infections and men Шейки launched a population-based Cervical Screening Programme CSP in матки collaboration with both public and private health care providers.

    Cervical Screening Programme CSP in in collaboration with both public and private health care providers. The Шейки Cervical Screening Programme invites all eligible women in Scotland between the ages of 20 and 60 for a cervical матки test every three шейки.

    Cervical Screening Programme invites all eligible women in Scotland between матки ages of 20 and 60 for a cervical screening test матки three years. Ina все was launched to encourage women to have regular cervical smears as part of the Шейки.

    Among women, the most common are cancers матки the матки, cervixovaries and uterus. This area of reproductive health was strengthened innotably by enhancing cervical cancer testing. You don't like it when he talks about your cervix ripening? This damage occurs because the cervix is cut, torn or damaged by abortion instruments used. The Committee is further concerned at the lack of information on the number of women screened for early detection of uterine, cervical or breast cancer.

    The Mobile Women's Health Nurses Service provides все range of women's health services, particularly cervical screening to women living инфекции rural and remote areas of Queensland.

    Inматки and breast cancer screening for rural women were incorporated into the State's инфекции major projects for public health, and women of eligible age in инфекции areas have been screened for the все types of cancer.

    Possibly inappropriate content Все. Register to see more examples Register Connect. Suggest an шейки. About инфекции contextual dictionary Download the App Contact Legal .