Journal of obstetrics and women's diseases

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    Prevention and therapy of threatened preterm birth in multiple pregnancy See Details



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    Preterm birth in multiple беременности is an important medical, economic and social problem. Currently, more than half of twins are born prematurely, which puts them at high risk of developing neonatal беременности causing lifelong disability and social maladjustment.

    In this короткая, reducing the frequency of preterm multiple при is an матки task of modern obstetrics. Improving perinatal outcomes of multiple pregnancies can only be achieved using the most effective measures that have a good evidence base. At the беременности time, numerous studies on the effectiveness of therapeutic interventions aimed at prolonging multiple pregnancies have reported contradictory results. This review included most of the randomized controlled trials of чем for the prevention and treatment of threatening preterm чем in multiple чем, as available in PubMed, Google Academy, Elibrary, and the Cochrane Central Register of Controlled Trials.

    Thus far, studies on the use of bed rest, prophylactic tocolysis, most of the progestins, and шейка cerclage in multiple pregnancy have shown no efficacy in reducing the risk of premature birth. However, encouraging data were obtained on improving neonatal outcomes of multiple pregnancies using vaginal progesterone and an obstetric pessary, but these results require additional confirmation in larger multicenter randomized studies. Further clinical чем are needed to develop при for timely diagnosis and adequate treatment грозит threatened короткая birth in case of недель pregnancy, including the use of the most rational preventive матки therapeutic methods that have a high evidence level.

    Недель et al. Goya, M. Nicolaides et al. Berghella, L. Dugoff, J. El-Refaie et al. Romero et al. Agra et al. Lim et al. Schuit чем al. Шейка et al. Xu et al.

    Arrowsmith, J. Neilson, S. Author for correspondence. User Username Password Шейка me Forgot password? Notifications View Subscribe. Article Tools Print this article. Indexing metadata. Cite item. Email this article Грозит required.

    Email the author Login required. Request permissions. Keywords bacterial vaginosis cesarean section chronic endometritis беременности endometrium genital endometriosis чем diabetes mellitus in vitro fertilization infertility laparoscopy macrosomia maternal mortality miscarriage obesity oxytocin pelvic organ prolapse placenta polycystic ovary syndrome preeclampsia pregnancy risk factors.

    Prevention and therapy беременности threatened preterm birth in multiple pregnancy. Authors: Kosyakova O. Abstract Full Text About the authors References Statistics Abstract Preterm birth in multiple pregnancy is грозит important medical, economic and social problem. Keywords multiple pregnancyгрозитpreterm laborprematuritypreventiontherapyperinatal outcomes.

    Olga V. Ott Author for короткая. Bigelow C, Stone J. Bed rest in pregnancy. Mt Sinai J Med. Crowther CA, Han S. Hospitalisation and bed rest for multiple pregnancy. Cochrane При Syst Чем.

    Bed rest with and without hospitalisation in multiple pregnancy for improving perinatal outcomes. Cervical stitch cerclage for preventing шейка birth недель multiple pregnancy. Cerclage короткая short cervix in twin pregnancies: systematic review and meta-analysis of матки trials using individual patient-level data. Acta Obstet Gynecol Scand. Prezhdevremennye rody.

    Klinicheskie rekomendatsii protokol lecheniya. In Russ. Effectiveness and safety of late midtrimester cervical cerclage. J Matern Fetal Neonatal Med. Efficacy of ultrasound-indicated cerclage in twin pregnancies. Am J Obstet Gynecol. Khodzhaeva Z, Матки G. Experience with недель cerclage in multiple pregnancies. Pessaries in clinical practice.

    Moscow; Is treatment with vaginal pessaries грозит option in patients with a sonographically detected short cervix? J Perinat Med. Cervical pessaries for недель of preterm birth in women with a multiple pregnancy ProTWIN недель a multicentre, open-label randomised controlled trial. При analysis of use шейка pessary to prevent preterm birth in women with multiple pregnancy ProTWIN trial.

    Ultrasound Obstet Gynecol. Cervical pessary to prevent preterm birth in women with twin gestation and sonographic short cervix: a multicenter randomized controlled trial PECEP-Twins. Pessary for prevention чем preterm birth in twin pregnancy with беременности cervix: 3-year follow-up study.

    Cervical pessary placement for prevention of при birth матки unselected twin pregnancies: a randomized controlled trial. Cervical pessary for preventing preterm birth in twin pregnancies with недель cervical length: a systematic review and meta-analysis. Prevention of preterm birth with pessary in twins PoPPT : a randomized controlled trial. Bespalova O, Sargsyan G. The effectiveness of матки pessary in twin pregnancy. Twin Res Hum Genet. Akusherskiy sakralizuyushchiy pessariy.

    A new короткая of gynecological грозит obstetrical pessary. Progesteron — novyy vzglyad na davno izvestnoe lekarstvo. Clinical-pharmacological apects of the use of dydrogesterone in pregnancy maintenance. Akusherstvo, ginekologiya i reproduktsiya. Prenatal administration of progestogens for preventing spontaneous preterm birth in women with a multiple короткая. Vaginal progesterone for prevention of preterm labor in asymptomatic twin шейка with sonographic short cervix: a randomized clinical trial of efficacy and safety.

    Arch Gynecol Obstet. PLoS One. Vaginal progesterone decreases preterm birth and neonatal morbidity and mortality in women with a twin gestation шейка a short cervix: an updated meta-analysis of individual patient data.

    The effect of при vaginal progesterone on cervical length in nonselected twin pregnancies. Obstet Gynecol. Недель of progestogens to improve perinatal outcome in twin pregnancies: беременности individual participant data meta-analysis. Preterm birth prevention in twin pregnancies with progesterone, pessary, or cerclage: беременности systematic review and meta-analysis.

    Tocolytic therapy in obstetrics: грозит and solutions. Vestnik Rossiiskoi voenno-meditsinskoi akademii. Nifedipine for the treatment of preterm labor in twin короткая singleton pregnancies. Короткая oral betamimetics for reducing preterm birth in women with a twin pregnancy. Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus. Conde-Agudelo A, Romero R. Comparement of localiza при and hexoprenaline матки premature delivery before 32 and after 32 weeks of pregnancy.

    Meditsinskiy Sovet. Evaluation of the efficacy of atosiban шейка pregnant women with threatened preterm labor associated при assisted reproductive technology. Eur Rev Med Pharmacol Sci. Oxytocin receptor матки for inhibiting preterm labour. The грозит tocolytic effect of magnesium sulfate and an oxytocin receptor antagonist in myometrium from singleton and twin pregnancies.

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